Fig. 6.

Predictive functional profiling of microbial communities in the liver tissues of patients with HCC. (A) Normalized heatmap of predicted KEGG pathways in HCC and adjacent normal tissues. N, Non-tumor group; T1, mUICC stage I; T2, mUICC stage II; T3, mUICC stage III. (B) Absolute value of Spearman’s correlation coefficient (|R|) between the hepatic microbial metabolic pathway, mUICC stage, and tumor size. The correlation results were deemed statistically significant at p < 0.05. Positive correlations are displayed in red, and negative correlations are in blue.