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. Author manuscript; available in PMC: 2024 Oct 31.
Published in final edited form as: Chem Biol Interact. 2016 Apr 7;259(Pt B):133–141. doi: 10.1016/j.cbi.2016.04.002

Figure 4.

Figure 4.

Dose-dependence of In Vivo Reactivation by ADOC. A) Reactivation of red blood cell acetylcholinesterase by ADOC administered at doses of 1.8, 10.0, 18.0, 32.0, or 56.0 mg/kg to animals exposed to 1xLD50 GB (▲), GF (▼) or VX (●). Whole blood reactivation displayed similar trends though absolute reactivation values differed (data not shown). B) Reactivation of mid-brain tissue acetylcholinesterase by ADOC administered at the indicated doses to animals exposed to GB (▲), GF (▼) or VX (●). All other tissues tested (brainstem, cerebellum, cortex, hippocampus, striatum, spinal cord, diaphragm, heart and skeletal muscle) displayed similar reactivation trends though absolute reactivation values differed (data not shown).