Table 4.
Visual and structural changes in eyes with different groups.
| Group A | Group B | Group C | |
|---|---|---|---|
| VA in LogMARa | |||
| Baseline vs. 3 M | − 0.10 (− 0.12 to − 0.03), P = 0.0001 | 0.00 (− 0.05 to 0.00), P = 0.2592 | 0.00 (− 0.04 to 0.11), P = 0.6250 |
| Baseline vs. 6 M | − 0.11 (− 0.14 to − 0.04), P = 0.0002 | − 0.04 (− 0.09 to 0.00), P = 0.1826 | − 0.04 (− 0.15 to 0.12), P = 0.9453 |
| Baseline vs. 12 M | − 0.09 (− 0.15 to − 0.04), P = 0.0013 | − 0.05 (− 0.11 to 0.03), P = 0.1791 | 0.00 (− 0.08 to 0.05), P = 0.8438 |
| CMT (μm)a | |||
| Baseline vs. 3 M | − 73.0 (− 104.5 to − 41.5), P < 0.0001 | − 99.0 (− 133.0 to − 70.5), P < 0.0001 | − 39.5 (− 95.0 to − 10.0), P = 0.0156 |
| Baseline vs. 6 M | − 54.25 (− 86.5 to − 34.0), P < 0.0001 | − 80.5 (− 118.5 to − 55.0), P < 0.0001 | − 51.0 (− 75.0 to − 26.0), P = 0.0156 |
| Baseline vs. 12 M | − 70.0 (− 96.0 to − 46.0), P < 0.0001 | − 112.0 (− 155.5 to − 83.0), P < 0.0001 | − 73.0 (− 164.0 to − 47.0), P = 0.0078 |
| Presence of SRFb | |||
| Baseline vs. 3 M | − 17.65% (− 26.71 to − 8.59), P = 0.0005 | − 28.99% (− 39.69 to − 18.28), P < 0.0001 | − 30.00% (− 58.40 to − 1.60), P = 0.2500 |
| Baseline vs. 6 M | − 18.18% (− 28.39 to − 7.97), P = 0.0018 | − 29.58% (− 40.89 to − 18.27), P < 0.0001 | − 30.00% (− 58.40 to − 1.60), P = 0.2500 |
| Baseline vs. 12 M | − 16.42% (− 25.29 to − 7.55), P = 0.0010 | − 26.39% (− 37.27 to − 15.50), P < 0.0001 | − 30.00% (− 58.40 to − 1.60), P = 0.2500 |
| Presence of IRCb | |||
| Baseline vs. 3 M | − 22.06% (− 31.91 to − 12.20), P = 0.0001 | − 34.78% (− 46.02 to − 23.54), P < 0.0001 | − 30.00% (− 58.40 to − 1.60), P = 0.2500 |
| Baseline vs. 6 M | − 10.61% (− 19.14 to − 2.07), P = 0.0391 | − 18.31% (− 28.87 to − 7.75), P = 0.0023 | − 20.00% (− 44.79 to 4.79), P = 0.5000 |
| Baseline vs. 12 M | − 16.42% (− 27.04 to − 5.79), P = 0.0074 | − 29.17% (− 40.35 to − 17.98), P < 0.0001 | − 40.00% (− 70.36 to − 9.64), P = 0.1250 |
LogMAR mean logarithm of the minimum angle of resolution; CMT central macular thickness; SRF sub-retinal fluid; IRC intra-retinal cyst.
aWilcoxon signed-rank test (Hodges-Lehmann median difference, 95% Confidence interval, Two-tailed probability) for LogMAR and CMT.
b McNemar test (95% CI, Exact probability (binomial distribution)) for Presence of SRF and IRC.
Significant values are in [bold].