Table 2.
Biochemical markers in patients with GSDIa
| Subject | Glucose (mmol/l) | Lactate (mmol/l) | Uric acid (μmol/l) | Total cholesterol (mmol/l) | HDL (mmol/l) | LDL (mmol/l) | Triglycerides (mmol/l) | AST (U/l) | ALT (U/l) | Insulin (μU/ml) | eGFR Ml/min/1,73 m2 | Microalbuminuri (mg/dl) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients with GSDIA | ||||||||||||
| P1 | 4.7 | 5.8 | 392.6 | 6.9 | 1.0 | 5.1 | 5.1 | 78 | 94 | 4.7 | 120 | 47.0 |
| P2 | 9.1 | 6.7 | 499.6 | 10.6 | 0.9 | 2.1 | 26.1 | 121 | 136 | 62.3 | 155 | 12.7 |
| P3 | 4.0 | 5.3 | 386.6 | 5.8 | 1.7 | 3.4 | 3.1 | 132 | 79 | 11.2 | 181 | 8.0 |
| P4 | 7.9 | - | 294.8 | 6.5 | 1.1 | 4.9 | 6.1 | 18 | 17 | 13.5 | 185 | 4.0 |
| P5 | 5.2 | 4.0 | 166.5 | 4.8 | 1.3 | 3.0 | 2.0 | 20 | 17 | 15.7 | 131 | 15.0 |
| P6 | 5.5 | 11.0 | 237.9 | 4.8 | 0.3 | 3.3 | 2.6 | 18 | 19 | 32.0 | 154 | 16.3 |
| P7 | 3.9 | 5.7 | 404.5 | 5.6 | 1.3 | 1.1 | 10.3 | 87 | 86 | 11.8 | 176 | 0.0 |
| P8 | 5.0 | 3.8 | 303.9 | - | - | - | - | 23 | 44 | 40.8 | - | 0.0 |
| P9 | 4.6 | 6.2 | 279.6 | 6.9 | 0.6 | - | 5.5 | 53 | 64 | 27.3 | 170 | 66.0 |
| P10 | 4.5 | 3.5 | 410.4 | 5.0 | 1.2 | 3.4 | 2.6 | 40 | 56 | 10.1 | 154 | - |
| P11 | 4.9 | 5.3 | 422.3 | 6.0 | - | - | 5.4 | 43 | 34 | - | 245 | - |
| P12 | 5.0 | 4.1 | 422.3 | 8.1 | 0.7 | 4.8 | 13.6 | 43 | 20 | - | - | - |
AST, aspartate aminotransferase; ALT, alanine aminotransferase; eGFR, estimated glomerular filtration rate; -, not available; SE, standard error.