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. 2024 Oct 4;29(6):697–708. doi: 10.1016/j.cstres.2024.10.001

Fig. 1.

Fig. 1

Effect of ebeiedinone and peimisine on BEAS-2B cells' resistance to CSE-induced oxidative damage. (a) The effect of CSE and ebeiedinone and peimisine (10, 20, and 40 μM) on ROS levels in BEAS-2B cells using 2′,7′-dichlorofluorescensin diacetate as a fluorescent probe. (b) It expresses the inhibition of ebeiedinone and peimisine on CSE-induced ROS production by relative fluorescence intensity. (c-f) The concentrations of MDA, 4-HNE, and SOD and GSH/GSSG ratio in BEAS-2B cells exposed to CSE for 24 h with ebeiedinone and peimisine (10, 20, and 40 μM) treated. The data are represented as the mean ± standard deviation of three independent experiments. ####P < 0.0001 compared with the control group. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001 compared with the CSE group. Abbreviation used: ns, not significant.