Table 2.
Disposable and drug costs per administration of ICI-B and ICI-P. ICI-B indicates conventional infusion of immune checkpoint inhibitors; ICI-P, immune checkpoint inhibitors administrated via an elastomeric pump
| Nivolumab 480 mg | Pembrolizumab 400 mg | |||||
|---|---|---|---|---|---|---|
| ICI-B | ICI-P | Incremental | ICI-B | ICI-P | Incremental | |
| Drug preparation disposables | ||||||
| Elastomeric pump | - | €43.60 | €43.60 | - | €43.60 | €43.60 |
| Sodium chloride | €0.42 | €0.42 | - | €0.42 | €0.42 | |
| Syringe and needles | €0.43 | €0.78 | €0.35 | €0.78 | €0.78 | €0.35 |
| Protective materials (e.g., sterile gloves) | €0.99 | €0.99 | - | €0.99 | €0.99 | - |
| Cleaning materials (e.g., isopropyl alcohol wipes) | €0.65 | €0.65 | - | €0.65 | €0.65 | - |
| Total drug preparation disposables | €2.76 | €46.71 | €15.75 | €2.76 | €18.51 | €15.75 |
| Drug administration disposables | ||||||
| IV infusion related (e.g., infusion line) | €11.16 | €2.83 | €8.33 | €8.28 | €2.83 | €5.45 |
| Protective materials (e.g., nonsterile gloves) | €0.21 | €0.21 | - | €0.21 | €0.21 | - |
| Sodium chloride | €0.42 | €0.08 | €0.34 | €0.42 | €0.08 | €0.34 |
| Others (e.g., disinfectant, bandages) | €1.60 | €1.60 | - | €1.60 | €1.60 | - |
| Total drug administration disposables | €13.39 | €3.91 | €9.48 | €10.51 | €3.91 | €6.60 |
| Total disposables costs | €16.15 | €50.62 | €34.47 | €13.27 | €50.62 | €37.35 |