Table 2.
Estimated odds ratio (95% CI) and variance (SE) of random hospital effect from logistic models of dichotomized outcomes, multinomial continuation-ratio logit model and logistic competing risks model
| Predictors | Dichotomized logistic | Multinomial continuation-ratio logit | Logistic competing risks | |||
|---|---|---|---|---|---|---|
| Death | NDI | NDI-free | Death | NDI if surviving | NDI by follow-up | |
| Birth weight (100 g) | 0.66 (0.62–0.71) | 1.05 (0.98–1.12) | 1.45 (1.36–1.56) | 0.66 (0.62–0.71) | 0.80 (0.74–0.87) | 1.06 (0.98–1.15) |
| Gestational age (weeks) | ||||||
| 22–23 | 2.76 (2.22–3.43) | 0.61 (0.48–0.78) | 0.43 (0.33–0.55) | 2.59 (2.09–3.22) | 1.23 (0.91–1.68) | 0.58 (0.43–0.78) |
| 24 | 1.46 (1.23–1.72) | 0.98 (0.83–1.16) | 0.72 (0.61–0.85) | 1.46 (1.24–1.72) | 1.20 (0.99–1.46) | 0.98 (0.80–1.20) |
| 25 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| Female | 0.57 (0.50–0.66) | 0.97 (0.84–1.12) | 1.85 (1.60–2.15) | 0.58 (0.50–0.67) | 0.66 (0.55–0.78) | 0.96 (0.80–1.16) |
| Singleton birth | 0.86 (0.74–1.01) | 1.05 (0.89–1.24) | 1.13 (0.95–1.34) | 0.85 (0.73–1.00) | 0.97 (0.79–1.18) | 1.03 (0.83–1.29) |
| Antenatal corticosteroids | 0.53 (0.43–0.65) | 1.28 (1.03–1.60) | 1.73 (1.35–2.21) | 0.52 (0.42–0.63) | 0.65 (0.49–0.87) | 1.21 (0.93–1.59) |
| Variance of random effect | 0.165 (0.065) | 0.126 (0.051) | 0.294 (0.110) | 0.147 (0.055) | 0.213 (0.064) | n.a. |
Footnote: Pr(Death) = 1-Pr(NDI)-Pr(NDI-free survival), Pr(NDI) = 1-Pr(Death)-Pr(NDI-free survival), Pr(NDI-free) = 1-Pr(Death)-Pr(NDI),
Pr(NDI if surviving) = 1-Pr(NDI-free if surviving), Pr(NDI by follow-up) = Pr(age of NDI in days < 22–24 months’ corrected age for prematurity)