. 2024 Oct 31;16:242. doi: 10.1186/s13195-024-01603-8

Table 1.

Descriptive statistics for CSO-PVS and BG-PVS volumes (in ml) for four annual visits, stratified by clinical groups. Group-level results included subjects who had at least three scans available (n = 503). We removed extreme values in volumes within the whole sample for each time point to lessen the influence of outliers and corrected estimates for age at the time of the scan

		*Clinical Group*
		CU	MCI	AD
	N	401	71	31
Baseline demographics	Females (%)	52.12	40.85	54.84
	Age (years)	70.2 ± 0.28	72.5 ± 0.69	74.3 ± 1.12
	Education (years)	14.9 ± 0.15	14.0 ± 0.37	12.9 ± 0.50
Baseline volume (ml)	CSO-PVS	1.91 ± 0.08	2.02 ± 0.20	1.56 ± 0.30
Baseline volume (ml)	BG-PVS	0.54 ± 0.02	0.60 ± 0.04	0.42 ± 0.06
12-month follow-up volume (ml)	CSO-PVS	2.06 ± 0.09	2.02 ± 0.21	1.81 ± 0.32
12-month follow-up volume (ml)	BG-PVS	0.57 ± 0.02	0.59 ± 0.04	0.44 ± 0.06
24-month follow-up volume (ml)	CSO-PVS	1.99 ± 0.09	2.28 ± 0.21	1.84 ± 0.33
24-month follow-up volume (ml)	BG-PVS	0.58 ± 0.02	0.63 ± 0.04	0.46 ± 0.06
36-month follow-up volume (ml)	CSO-PVS	2.07 ± 0.11	2.21 ± 0.26	1.66 ± 0.49
36-month follow-up volume (ml)	BG-PVS	0.57 ± 0.02	0.62 ± 0.05	0.42 ± 0.09
Annual change^a of PVS (in ml/year)	CSO-PVS	0.04 ± 0.03	0.08 ± 0.04	0.03 ± 0.07
Annual change^a of PVS (in ml/year)	BG-PVS	0.01 ± 0.00	0.01 ± 0.01	0.002 ± 0.01
Annual change^a of PVS from baseline (in %/year)	CSO-PVS	2.11	4.13	1.98
Annual change^a of PVS from baseline (in %/year)	BG-PVS	1.82	1.68	0.46

Annotations. Mean ± standard error;

^aChange of PVS volumes per AD biomarker group was estimated based on linear approximations