Fig. 5.

Predicting binding affinity for low variation compounds using different feature types and their combinations. The bar plot presents PCCs for predicting the binding affinity of low variation compounds using various feature types: FP (ECFP4), Seq (protein sequence encoding), and IFP. The first three bars represent individual features: FP, Seq, and IFP. The following three bars show combinations of two features: FP + Seq, FP + IFP, and Seq + IFP. The rightmost bar represents the combination of all three features: FP + Seq + IFP. The height of each bar indicates the PCC value, with specific values annotated above each bar for clarity.