Table 1.
Baseline characteristics comparison between two groups
| Variable | Patients (n = 31) | Controls (n = 31) | Total (n = 62) | p-value¶ |
|---|---|---|---|---|
| •Demographics | ||||
| Male | 71% (22) | 52% (16) | 61% (38) | 0.192 |
| Age, years | 50 [17] | 58 [14] | 55 [18] | 0.051 |
| Overweight & obese | 61% (19) | 10% (3) | 35% (22) | < 0.001* |
| Metabolic syndrome | 29% (9) | 10% (3) | 19% (12) | 0.106 |
| • Anthropometrics | ||||
| BMI, kg/m2 | 25 [6] | 23 [4] | 24 [5] | < 0.001* |
| WC, cm | 96 [21] | 81 [15] | 89 [18] | < 0.001* |
| SCD, mm | 16 [7] | 11 [7] | 15 [8] | < 0.001* |
| • Liver disease etiology | ||||
| Viral (CHB, CHC) | 35% (11) | - | - | - |
| MASLD | 45% (14) | - | - | - |
| ALD | 3% (1) | - | - | - |
| Coexistent CHB & ALD | 10% (3) | - | - | - |
| Coexistent CHB & MASLD | 6% (2) | - | - | - |
| • LSM in the supine position | ||||
| LS, kPa | 13.1 [7] | 4.6 [1] | 7.8 [9] | < 0.001* |
| IQR/median, % | 24 [13] | 26 [13] | 25 [12] | 0.368 |
| Success rate§, % | 100 [0]/100 ± 0 | 100 [0]/97 ± 6 | 100 [0]/99 ± 4 | 0.005* |
| • LSM in the seated position | ||||
| LS, kPa | 12.7 [7] | 5.1 [2] | 7.4 [8] | < 0.001* |
| IQR/median, % | 24 [13] | 30 [23] | 25 [18] | 0.208 |
| Success rate§, % | 100 [7]/96 ± 9 | 100 [0]/99 ± 2 | 100 [0]/98 ± 6 | 0.072 |
| • LSM in the standing position | ||||
| LS, kPa | 13.0 [7] | 6.2 [2] | 7.9 [7] | < 0.001* |
| IQR/median, % | 26 [20] | 30 [19] | 28 [18] | 0.559 |
| Success rate§, % | 100 [0]/99 ± 3 | 100 [0]/99 ± 3 | 100 [0]/99 ± 3 | 0.687 |
All data are median [IQR] or % (n), unless otherwise indicated
ALD Alcoholic liver disease, BMI Body mass index, CHB Chronic hepatitis B, CHC Chronic hepatitis C, LS Liver stiffness, LSM Liver stiffness measurement, MASLD Metabolic dysfunction-associated steatotic liver disease, WC Waist circumference, SCD Skin-liver capsule distance
¶Quantitative variables between groups were compared by Mann–Whitney U test; categorical variables were compared by Fisher’s exact test
§Data are presented as median [IQR] / mean ± standard deviation
* p < 0.05