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. 2024 Oct 31;24:386. doi: 10.1186/s12876-024-03473-8

Table 2.

Factors associated with LS measured under three posture conditions in univariate analyses

Characteristics Supine LSM Seated LSM Standing LSM
rs p rs p rs p
Age (per year) - 0.104 - 0.106 –0.270 0.034*
Weight (kg) 0.410  < 0.001* 0.308 0.015* 0.322 0.011*
BMI (kg/m2) 0.425  < 0.001* 0.268 0.035* - 0.086
SCD (mm) 0.370 0.003* 0.277 0.029* 0.260 0.041*
WC (cm) 0.467  < 0.001* 0.369 0.003* 0.345 0.006*
CAP value (dB/m) - 0.154 - 0.624 - 0.648
Median [IQR] p Median [IQR] p Median [IQR] p
Steatosis

Absent, 6.5 [11];

Present, 9.2 [7]

 0.849 Absent, 7.8 [10]; Present, 7.3 [6] 0.877 Absent, 7.2 [10]; Present, 7.9 [6] 0.767
Sex

Male, 10.2 [10];

Female, 6.3 [8]

 0.193

Male, 8.3 [9];

Female, 7.0 [6]

 0.127

Male, 9.2 [9];

Female, 6.6 [6]

 0.066
Overweight / obesity

Absent, 5.5 [6];

Present, 12.2 [5]

  < 0.001* Absent, 6.8 [4]; Present, 11.5 [7] 0.008* Absent, 6.7 [4]; Present, 12.0 [7] 0.017*
Hypertension

Absent, 6.2 [9];

Present, 10.6 [9]

 0.187 Absent, 7.3 [8]; Present, 8.0 [10] 0.464 Absent, 7.9 [8]; Present, 9.5 [9] 0.330
Type 2 DM

Absent, 5.8 [8];

Present, 11.8 [5]

 0.013* Absent, 6.9 [7]; Present, 11.1 [7] 0.032* Absent, 7.1 [7]; Present, 11.3 [7] 0.111
Dyslipidaemia

Absent, 6.2 [9];

Present, 10.2 [7]

 0.627 Absent, 7.2 [9]; Present, 8.0 [7] 0.527 Absent, 7.9 [7]; Present, 9 [7] 0.889
Metabolic syndrome

Absent, 6.2 [9];

Present, 11.0 [9]

 0.119 Absent, 7.3 [7]; Present, 10.5 [7] 0.128 Absent, 7.5 [7]; Present, 9.9 [9] 0.293
Biopsy-proven fibrosis

No, 4.6 [1];

Yes, 13.1 [7]

  < 0.001*

No, 5.1 [2];

Yes, 12.7 [7]

  < 0.001*

No, 6.2 [2];

Yes, 13.0 [7]

  < 0.001*

Age, weight, BMI, SCD, WC waist circumference were analysed by Spearman's correlation test; sex, overweight / obesity, presence of steatosis, hypertension, DM, dyslipidaemia, metabolic syndrome, and a history of biopsy-proven liver fibrosis were analysed by unpaired t-test or Mann–Whitney U test, where appropriate

* p ≤ 0.05

BMI Body mass index, SCD Skin-liver capsule distance, DM Diabetes mellitus, WC Wwaist circumference, CAP Controlled attenuation parameter, rs Spearman's rank correlation coefficient