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[Preprint]. 2024 Oct 14:arXiv:2410.10911v1. [Version 1]

Figure 3.

Figure 3.

Results of the miss-matched DNA experiment for determination of specificity. A) shows the average intensity at major UCNP peaks for each type of miss-match DNA sequence. The target DNA shows the maximum quenching compared to the negative control, measured at 64.4 %, while the mmP1P2, where the 12 miss-match bases are on the UCNP side, and 12 miss-match bases are on the AuNp side as well, shows only 39.3 %. (b) shows the zoomed-in view for 523 nm and 457 nm results, both showing much lower sensitivity compared to 550 nm.