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. 2024 Oct 31;18(10):e0012566. doi: 10.1371/journal.pntd.0012566

Table 3. Characteristics of P. vivax recurrences detected between January 2013 and December 2015.

Cahuide Lupuna Total
N % N % N %
Number of individuals 118 100 267 100 385 100
Recurrences detected by PCR
 Individuals with recurrences 90 76.3 223 83.5 313 81.3
  1 recurrence 41 45.6 48 21.5 89 28.4
  2 recurrences 14 15.6 32 14.3 46 14.7
  3 recurrences 13 14.4 40 17.9 53 16.9
  4+ recurrences 22 24.4 103 46.2 125 39.9
 Total number of recurrences 233 835 1068
 Number of recurrences/individuals (Median [IQR]; max.) 1 [1–3], 14 3 [1–4], 14 2 [1–4], 14
 Time to detect recurrences
  0–90 days 42 18.0 91 10.9 133 12.5
  90–180 days 47 20.2 128 15.3 175 16.4
  >180 days 144 61.8 616 73.8 760 71.2
Recurrences detected by microscopy
 Individuals with recurrences 48 40.7 161 60.3 209 54.3
  1 recurrence 31 64.6 60 37.3 91 43.5
  2 recurrences 8 16.7 38 23.6 46 22.0
  3 recurrences 6 12.5 29 18.0 35 16.7
  4+ recurrences 3 6.3 34 21.1 37 17.7
 Total number of recurrences 82 385 467
 Number of recurrences/individuals (Median [IQR]; max.) nnn[0–1], 8 1 [0–2], 7 1 [0–2], 8
 Time to detect recurrences
  0–90 days 26 31.7 60 15.6 86 18.4
  90–180 days 15 18.3 61 15.8 76 16.3
  >180 days 41 50.0 264 68.6 305 65.3
Number of individuals 90 100 223 100 313 100
Asymptomatic recurrences
 Individuals with recurrences 76 84.4 183 82.1 259 82.7
  1 recurrence 37 48.7 67 36.6 104 40.2
  2 recurrences 20 26.3 45 24.6 65 25.1
  3 recurrences 6 7.9 25 13.7 31 12.0
  4+ recurrences 13 17.1 46 25.1 59 22.8
 Total number of recurrences detected 162 489 651
 Number of recurrences/individuals (Median [IQR]; max.) 2 [1–2.25], 9 2 [1–3.5], 12 2 [1–3], 12
 Time to detect recurrences
  0–90 days 26 16.0 44 9.0 70 10.8
  90–180 days 33 20.4 68 13.9 101 15.5
  >180 days 103 63.6 377 77.1 480 73.7
Symptomatic recurrences
 Individuals with recurrences 45 50.0 173 77.6 218 69.6
  1 recurrence 34 75.6 80 46.2 114 52.3
  2 recurrences 6 13.3 46 26.6 52 23.9
  3 recurrences 4 8.9 30 17.3 34 15.6
  4+ recurrences 1 2.2 17 9.8 18 8.3
 Time to detect recurrences 71 346 417
 Number of recurrences/individuals (Median [IQR]; max.) 1 [1–1], 13 2 [1–3], 9 2 [1–3], 13
Time to detect recurrences
  0–90 days 16 22.5 47 13.6 63 15.1
  90–180 days 14 19.7 60 17.3 74 17.7
  >180 days 41 57.7 239 69.1 280 67.1
Submicroscopic recurrences
 Individuals with recurrences 73 81.1 163 73.1 236 75.4
  1 recurrence 39 53.4 59 36.2 98 41.5
  2 recurrences 15 20.5 32 19.6 47 19.9
  3 recurrences 6 8.2 27 16.6 33 14.0
  4+ recurrences 13 17.8 45 27.6 58 24.6
 Total number of recurrences 151 450 601
 Number of recurrences/individuals (Median [IQR]; max.) 1 [1–3], 9 2 [1–4], 11 2 [1–3], 10
 Time to detect recurrences
  0–90 days 9 6.0 31 6.9 40 6.7
  90–180 days 13 8.6 67 14.9 80 13.3
  >180 days 45 29.8 352 78.2 397 66.1