Figure 2.

Haplotype blocks identified in 1,962 individuals carrying at least one rs10423769_A allele using Haploview 4.2 and ADSP. Lines between blocks indicate co-occurrence of adjacent haplotypes in individuals with line thickness representing frequency of co-occurrence across individuals. Haplotype block frequencies are shown in the right of each block (≥ 0.05). Multiallelic D' is shown on the bottom of crossing areas, which represents the level of recombination between blocks. Blocks with D' > 0.8 were considered the same haplotype. Rs10423769 is marked by an orange box. The 21kb (chr19:43099521-43120243) minimum shared haplotype is marked by a red box and the 11 kb extended haplotype (chr19:43121359- 43132912) is marked by blue boxes.