Table 4. Comparisons of clinical characteristics and OCTA parameters in PWMH.
| Fazekas scales | P value | Scheltens scales | P value | |||
|---|---|---|---|---|---|---|
| ≤1 | >1 | ≤2 | >2 | |||
| n | 18 | 31 | 19 | 30 | ||
| Age (years) | 64.50(6.35) | 67.26(6.82) | 0.168 | 64.11(6.40) | 67.60(6.66) | 0.076 |
| Sex (male/female) | 9/9 | 15/16 | 0.913 | 9/10 | 15/15 | 0.858 |
| Hypertension (%) | 8(44.4) | 12(38.7) | 0.694 | 8(42.1) | 12(40) | 0.884 |
| Diabetes (%) | 1(5.6) | 8(2.85) | 0.078 | 1(5.3) | 8 (26.7) | 0.059 |
| Hyperlipidemia (%) | 9(50) | 15(48.8) | 0.913 | 10(52.6) | 14(46.7) | 0.684 |
| Heart diseases (%) | 1(5.6) | 2(6.5) | 0.9 | 1(5.3) | 2(6.7) | 0.842 |
| Present smokers (%) | 3(16.7) | 7(22.6) | 0.62 | 3(15.8) | 7(23.3) | 0.523 |
| Present drinkers (%) | 3(16.7) | 4(12.9) | 0.717 | 3(15.8) | 4(13.3) | 0.811 |
| BMI | 23.05(3.14) | 23.31(3.12) | 0.788 | 23.13(3.06) | 23.27(3.17) | 0.877 |
| MoCA | 26.00(5.50) | 27.00(4.00) | 0.755 | 26.50(5.50) | 27.00(4.00) | 0.938 |
| Eyesight | 1.000(0.350) | 0.775(0.463) | 0.131 | 1.000(0.325) | 0.750(0.475) | 0.141 |
| IOP | 13.90(2.63) | 13.98(3.43) | 0.751 | 13.88(2.34) | 14.15(3.55) | 0.627 |
| Ocular axis | 23.75(1.01) | 24.01(1.27) | 0.472 | 23.77(0.99) | 24.00(1.30) | 0.508 |
| Vessel density | ||||||
| Peripapillary | ||||||
| Whole | 17.55(2.13) | 16.65(2.30) | 0.068 | 17.58(2.19) | 16.55(2.28) | 0.029 |
| Inner ring | 18.87(2.89) | 16.88(2.16) | 0.012 | 18.63(2.73) | 16.87(2.08) | 0.007 |
| Temporal | 18.95(3.73) | 16.38(3.70) | 0.013 | 18.83(3.61) | 16.25(3.48) | 0.008 |
| Superior | 19.00(1.70) | 17.95(2.83) | 0.003 | 18.95(1.58) | 17.90(2.85) | 0.003 |
| Nasal | 17.45(4.85) | 16.38(4.30) | 0.163 | 17.40(4.43) | 16.15(4.33) | 0.12 |
| Inferior | 18.95(2.28) | 17.45(2.48) | 0.022 | 19.00(2.21) | 17.20(2.48) | 0.011 |
| Outer ring | 17.90(2.74) | 17.20(3.01) | 0.239 | 18.02(2.74) | 17.19(3.03) | 0.114 |
| Temporal | 18.65(2.58) | 17.58(2.90) | 0.236 | 18.68(2.46) | 17.50(3.13) | 0.139 |
| Superior | 18.35(1.95) | 18.00(2.71) | 0.219 | 18.60(1.93) | 18.00(2.73) | 0.168 |
| Nasal | 16.73(3.41) | 16.10(4.45) | 0.419 | 16.75(3.23) | 15.90(4.18) | 0.232 |
| Inferior | 18.60(2.65) | 18.30(2.88) | 0.278 | 18.83(2.48) | 18.25(2.90) | 0.178 |
| Macula | ||||||
| Whole | 13.78(5.18) | 12.90(5.29) | 0.924 | 14.00(5.40) | 12.80(4.63) | 0.666 |
| Inner ring | 13.24(4.25) | 13.24(5.97) | 0.965 | 13.31(4.59) | 13.23(5.68) | 0.63 |
| Temporal | 13.50(5.83) | 12.05(6.65) | 0.514 | 13.83(6.03) | 11.80(6.55) | 0.288 |
| Superior | 12.70(4.85) | 12.88(6.48) | 0.833 | 12.83(5.19) | 12.85(6.40) | 0.533 |
| Nasal | 12.33(6.73) | 13.73(6.99) | 0.418 | 12.45(6.75) | 12.75(6.50) | 0.666 |
| Inferior | 12.67(3.18) | 12.61(4.89) | 0.965 | 12.94(3.32) | 12.43(4.87) | 0.689 |
| Outer ring | 14.86(4.33) | 13.85(4.83) | 0.615 | 14.93(4.22) | 13.65(4.91) | 0.441 |
| Temporal | 13.10(4.73) | 12.05(7.63) | 0.345 | 13.60(3.96) | 11.28(8.24) | 0.256 |
| Superior | 15.20(5.03) | 13.65(3.98) | 0.539 | 15.35(5.21) | 13.55(3.56) | 0.339 |
| Nasal | 16.45(3.24) | 16.45(3.91) | 0.702 | 16.85(4.35) | 16.35(3.95) | 0.911 |
| Inferior | 14.17(2.70) | 13.58(3.74) | 0.572 | 14.34(2.71) | 13.44(3.74) | 0.39 |
| Perfusion density | ||||||
| Peripapillary | ||||||
| Whole | 0.442(0.057) | 0.418(0.066) | 0.073 | 0.443(0.059) | 0.416(0.064) | 0.03 |
| Inner ring | 0.489(0.084) | 0.439(0.065) | 0.025 | 0.483(0.078) | 0.439(0.060) | 0.017 |
| Temporal | 0.459(0.082) | 0.392(0.086) | 0.013 | 0.451(0.080) | 0.391(0.078) | 0.009 |
| Superior | 0.501(0.058) | 0.473(0.075) | 0.015 | 0.500(0.057) | 0.472(0.080) | 0.011 |
| Nasal | 0.477(0.110) | 0.452(0.131) | 0.17 | 0.475(0.102) | 0.451(0.131) | 0.131 |
| Inferior | 0.499(0.053) | 0.470(0.077) | 0.023 | 0.500(0.049) | 0.469(0.076) | 0.016 |
| Outer ring | 0.452(0.074) | 0.429(0.081) | 0.244 | 0.454(0.080) | 0.428(0.079) | 0.114 |
| Temporal | 0.454(0.066) | 0.426(0.075) | 0.203 | 0.456(0.065) | 0.424(0.080) | 0.134 |
| Superior | 0.468(0.042) | 0.467(0.077) | 0.314 | 0.469(0.042) | 0.460(0.076) | 0.197 |
| Nasal | 0.427(0.094) | 0.405(0.121) | 0.426 | 0.428(0.091) | 0.402(0.116) | 0.211 |
| Inferior | 0.470(0.070) | 0.462(0.079) | 0.376 | 0.475(0.068) | 0.461(0.079) | 0.204 |
| Macula | ||||||
| Whole | 0.336(0.135) | 0.310(0.134) | 0.898 | 0.344(0.144) | 0.308(0.117) | 0.62 |
| Inner ring | 0.303(0.105) | 0.306(0.148) | 0.991 | 0.309(0.113) | 0.305(0.142) | 0.67 |
| Temporal | 0.301(0.086) | 0.270(0.124) | 0.371 | 0.308(0.088) | 0.265(0.123) | 0.21 |
| Superior | 0.304(0.114) | 0.296(0.162) | 0.833 | 0.305(0.120) | 0.296(0.156) | 0.518 |
| Nasal | 0.285(0.152) | 0.316(0.177) | 0.4 | 0.285(0.161) | 0.291(0.176) | 0.628 |
| Inferior | 0.294(0.081) | 0.295(0.118) | 0.965 | 0.301(0.084) | 0.291(0.118) | 0.74 |
| Outer ring | 0.366(0.113) | 0.333(0.131) | 0.66 | 0.367(0.112) | 0.328(0.133) | 0.464 |
| Temporal | 0.317(0.116) | 0.285(0.193) | 0.393 | 0.329(0.097) | 0.269(0.207) | 0.28 |
| Superior | 0.376(0.126) | 0.322(0.116) | 0.649 | 0.381(0.129) | 0.321(0.108) | 0.399 |
| Nasal | 0.399(0.084) | 0.386(0.122) | 0.67 | 0.412(0.113) | 0.386(0.129) | 0.888 |
| Inferior | 0.345(0.074) | 0.327(0.099) | 0.526 | 0.349(0.074) | 0.324(0.099) | 0.36 |
| FAZ area (mm2) | 0.234(0.075) | 0.223(0.084) | 0.652 | 0.236(0.074) | 0.221(0.085) | 0.534 |
| FAZ perimeter(mm) | 2.02(0.31) | 1.94(0.39) | 0.486 | 2.03(0.31) | 1.93(0.39) | 0.357 |
| FAZ circularity | 0.697(0.028) | 0.702(0.044) | 0.642 | 0.696(0.028) | 0.703(0.045) | 0.483 |
BMI: Body Mass Index; MoCA: Montreal Cognitive Assessment; IOP: intra-ocular pressure; FAZ: Foveal Avascular Zone