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. 2024 Oct 31;19(10):e0308406. doi: 10.1371/journal.pone.0308406

Table 2. Comparison of participant characteristics with knowledge and perception of rational medicine use.

Characteristic RUM Knowledge RUM Perception
Good n (%) Poor n (%) *p-value Good n (%) Neutral n (%) Poor n (%) δp-value
Drug bulletin as reference 0.174 0.169
Yes 99 (68.3) 46 (31.7) 125 (86.5) 10 (6.9) 10 (6.9)
No 27 (57.5) 20 (42.6) 39 (83.0) 7 (14.9) 1 (2.1)
STG as reference 0.001 0.315
Yes 100 (72.5) 38 (27.5) 121 (87.7) 10 (7.2) 7 (5.1)
No 26 (48.2) 28 (51.9) 43 (79.6) 7 (13.0) 4 (7.4)
BNF as reference 0.001 0.609
Yes 67 (77.9) 19 (22.1) 74 (86.0) 6 (7.0) 6 (7.0)
No 59 (55.7) 47 (44.3) 90 (84.9) 11 (10.4) 5 (4.7)
Medscape as reference 0.057 0.046
Yes 58 (73.4) 21 (26.6) 66 (83.5) 11 (13.9) 2 (2.5)
No 68 (60.2) 45 (39.8) 98 (86.7) 6 (5.3) 9 (8.0)
Reference source accessible 0.323 0.026
Yes 89 (67.9) 42 (32.1) 118 (90.1) 8 (6.1) 5 (3.8)
No 37 (60.7) 24 (39.3) 46 (75.4) 9 (14.8) 6 (9.8)
Drug bulletin updates 0.001 0.007
Never 35 (64.8) 19 (35.2) 48 (88.9) 5 (9.3) 1 (1.9)
Quarterly 45 (69.2) 20 (30.8) 60 (92.3) 2 (3.1) 3 (4.6)
Monthly 34 (82.9) 7 (17.1) 36 (87.8) 3 (7.3) 2 (4.9)
Annually 12 (37.5) 20 (62.5) 20 (62.5) 7 (21.9) 5 (15.6)
Age (years) 0.934 0.456
20–25 13 (61.9) 8 (38.1) 16 (76.2) 4 (19.0) 1 (4.8)
26–35 62 (64.6) 34 (35.4) 83 (86.5) 7 (7.3) 6 (6.3)
36–45 39 (67.2) 19 (32.8) 52 (89.7) 3 (5.2) 3 (5.2)
45–55 12 (70.6) 5 (29.4) 13 (76.5) 3 (17.6) 1 (5.9)
Level of Hospital 0.047 0.284
Primary 118 (67.8) 56 (32.2) 149 (85.6) 14 (8.0) 11 (6.3)
Secondary 8 (44.4) 10 (55.6) 15 (83.3) 3 (16.7) 0 (0.0)
Type of prescriber 0.001 0.011
Doctor 37 (78.7) 10 (21.3) 46 (97.9) 1 (2.1) 0 (0.0)
Medical intern 3 (42.9) 4 (57.1) 5 (62.5) 3 (37.5) 0 (0.0)
Physician assistant 41 (73.2) 15 (26.8) 48 (85.7) 4 (7.1) 4 (7.1)
Physician assistant intern 23 (76.7) 7 (23.3) 25 (86.2) 3 (10.3) 1 (3.4)
Nurse 17 (47.2) 19 (52.8) 28 (77.8) 5 (13.9) 3 (8.3)
Others 5 (31.3) 11 (68.7) 12 (75.0) 1 (6.3) 3 (18.8)
Years of experience 0.167 0.172
≤3 years 63 (65.6) 33 (34.4) 75 (78.1) 11 (11.5) 10 (10.4)
>3–6 years 20 (58.8) 14 (41.2) 32 (94.1) 2 (5.9) 0 (0.0)
>6–10 years 22 (59.5) 15 (40.5) 34 (91.9) 2 (5.4) 1 (2.7)
>10 years 21 (84.0) 4 (16.0) 23 (92.0) 2 (8.0) 0 (0.0)
State of DTC 0.004 0.394
Functional 39 (83.0) 8 (17.0) 43 (91.5) 2 (4.3) 2 (4.3)
Nonfunctional 86 (59.7) 58 (40.3) 121 (83.4) 15 (10.3) 9 (6.2)

RUM = rational use of medicine; DTC = drugs and therapeutic committee; STG = standard treatment guidelines; BNF = British National Formulary

*p-value was determined using the chi-squared statistic.

δp-value was determined using Fisher’s exact test