FIG 1.

Flow diagram. In the treatment-naïve subgroup, discontinuations labeled as other included one patient who refused medication because of low back pain, one patient who had two medication interruptions in a relatively short interval (one because of severe acute coronary syndrome and one because of increased creatinine), and one patient who was assessed as unfit for further trial participation because of persistently reduced creatinine clearance. AE, adverse event; NSCLC, non–small cell lung cancer; METex14, MET exon 14 skipping.