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. 2024 Nov 1;134(21):e178949. doi: 10.1172/JCI178949

Figure 1. Outline of the study and flow cytometry analysis of MS monocytes.

Figure 1

(A) Schematic overview of the experimental model from MS- or HD-derived peripheral blood monocytes, mDCs, and tolDCs. Created with BioRender (biorender.com). (B) Flow cytometry representative figures and box plots reporting different percentages of classical (CD14++CD16–), intermediate (CD14+CD16+), and non-classical (CD14+CD16++) monocytes among MS patients and HDs, with respect to total monocytes as parent gate (top row), or reporting the percentage of CD45RA+ (middle row) or CD40+ (bottom row) with respect to classical, intermediate, or non-classical monocytes. P values from Mann-Whitney tests are shown in cases of statistical significance. n = 7 in each sample group.