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. 2024 Oct 30;11(6):e200320. doi: 10.1212/NXI.0000000000200320

Table 1.

Sample Usage and Clinical Data

Participant A B C D E F G
CSF collection time point Early Late Early Late Early Late Early Late Early Early Late Late
Flow + + + + + + + +
scRNA + + + + + + + +
Clinical presentation Headaches, communicating hydrocephalus Communicating hydrocephalus, meningitis Obstructive hydrocephalus, meningitis Difficulty walking, spinal cord compression Seizures Ischemic stroke Headaches, communicating hydrocephalus
New diagnosis vs. recurrence New Diagnosis Recurrence Reccurence Recurrence New Diagnosis Recurrence Recurrence
On albendazole and/or praziquantel Yes Yes No Yes Yes Yes No Yes No No Yes Yes
Time on anthelmintics (mo) <1 4 3 1 6 60 3 8
Dexamethasone equivalent (mg) 7.5 9 0 0.9 1.5 0.8 0 0 18 1.1 4 0.8
Steroid-sparing agents Etanercept Methotrexate Etanercept, methotrexate
T. solium qPCR (Cq) 19.6 25.6 32.8 28.2 22.1 24.2 35.8 29 40 33.2 27.1 34.3
Taenia antigena (ng/mL) 17,104 8,207 >4,000 20 2,239 47 6,580 527 21 10 0 0

(—) Indicated field not applicable.

a

Capture ELISA TsG10, commercial ELISA, or B60/158 Luminex assay.