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. 2024 Oct 18;69:1607676. doi: 10.3389/ijph.2024.1607676

TABLE 2.

Meta-analysis results and characteristics of studies informing the associations between long-term exposure to ozone (O3) (per 10 μg/m3 increase) and mortality outcomes (Global, 2023-2024).

A) Annual O3
N RR (95% CI) I2 (%) 80% prediction interval Sample size Age (years) Median of O3 (min – max)
All-cause 9 1.01 (0.96, 1.06) 92 (0.91, 1.11) 1,622,831 >30 60.6 (42.3–94.3)
Respiratory disease 6 1.05 (1.02,1.08) 65 (1.00, 1.09) 1,544,274 >30 70.4 (50.8–94.3)
COPD 2 1.06 (1.03, 1.08) 25 - 1,217,826 >30 74.87–76.44*
ALRI 2 1.04 (0.97, 1.11) 80 - 1,217,826 >30 74.87–76.44*
B) Peak/warm season O3
N RR (95% CI) I2 (%) 80% Prediction Interval Sample size Age (years) Median of O3 (min – max)
All-cause 12 1.01 (0.97, 1.04) 98 (0.92, 1.10) 107,896,036 >18 90.6 (74.9–106.6)
Respiratory disease 9 1.01 (0.98, 1.03) 92 (0.95, 1.06) 57,107,136 >25 85 (74.9–109.8)
COPD 7 1.00 (0.96, 1.04) 95 (0.92, 1.09) 56,668,296 >25 85 (74.9–109.8)
ALRI 4 1.02 (0.99, 1.04) 88 (0.97, 1.07) 23,702,383 >30 87.9 (74.9–109.8)

N = number of studies; min: minimum; max: maximum.