Fig. 6.

Combined therapy with rAd.DCN and NK cells does not increase the toxicity in xenograft model. a Results of serum LDH assay in mice at the endpoint of the experiment. b Detection of ALT in serum 24 h after NK cell infusion in the first and second treatment cycles and at the end of the experiment. One-way ANOVA was used for comparisons between multiple groups. c Representative images of HE staining of liver tissues. Scale bar = 50 µm. d Representative images of histochemistry staining of adenovirus in liver tissues. Scale bar = 100 µm. Data are presented as mean ± SD (n = 7). **p < 0.01; ***p < 0.001