Table 3.
The roles of GM-CSF in colitis models
| Article | Colitis model | Method | The role of GM-CSF | The role of IL-23 | Ref |
|---|---|---|---|---|---|
| Pearson et al. | CD40 agonistic antibody | Anti-GM-CSF Ab | Inflammatory | Inflammatory | [55] |
| Griseri et al. | Naïve T transfer | Anti-GM-CSF Ab | Inflammatory | Inflammatory | [76] |
| Griseri et al. | Hh + anti-IL-10R |
Csf2rb−/− or anti-GM-CSF Ab |
Inflammatory | Inflammatory | [77] |
| Han et al. | NSAID-induced ileitis |
Csf2−/−, Csf2rb−/−or Anti-GM-CSF Ab |
Protective | [81] | |
| Sainathan et al. | DSS | Inject recombinant mouse GM-CSF | Protective | [78] | |
| Xu et al. | DSS | Csf2−/− | Protective | [79] | |
| Egea et al. | DSS | Csf2−/− | Protective | [80] |