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. 2024 Oct 8;21(11):1183–1200. doi: 10.1038/s41423-024-01218-x

Table 3.

The roles of GM-CSF in colitis models

Article Colitis model Method The role of GM-CSF The role of IL-23 Ref
Pearson et al. CD40 agonistic antibody Anti-GM-CSF Ab Inflammatory Inflammatory [55]
Griseri et al. Naïve T transfer Anti-GM-CSF Ab Inflammatory Inflammatory [76]
Griseri et al. Hh + anti-IL-10R

Csf2rb−/− or

anti-GM-CSF Ab

Inflammatory Inflammatory [77]
Han et al. NSAID-induced ileitis

Csf2−/−, Csf2rb−/−or

Anti-GM-CSF Ab

Protective [81]
Sainathan et al. DSS Inject recombinant mouse GM-CSF Protective [78]
Xu et al. DSS Csf2−/− Protective [79]
Egea et al. DSS Csf2−/− Protective [80]