TABLE 5.

List of differentially regulated proteins in 5-FU treated group vs. control group. Positive fold-change value denotes up-accumulation and negative fold change value denotes down-accumulation in comparison with control.

Gene symbol	Protein name	p-value (FDR)	Fold change (log2 vs. control)	Biological process
Apoa2	Apolipoprotein A-II	0.004158	0.77	Lipid transport and metabolism, retinoid transport, chylomicron remodeling
Mt-1	Metallothionein-1	0.012015	0.67	Cellular homeostasis of metal ions, signal transduction mediated by nitric oxide
Ptma	Prothymosin alpha	0.016023	0.51	Histone modification, negative regulation of apoptosis, immune response
Ces1c	Carboxylesterase 1C	0.023659	0.45	Lipid catabolism, response to metal ions
Rpl29	Large ribosomal subunit protein L29	0.006359	0.42	Translation
Cavin2	Caveolae-associated protein 2	0.021712	0.40	Regulation of transcription, lipid metabolism
Cdk11b	Cyclin-dependent kinase 11B	0.013975	0.37	Cell cycle
Dnajc3	DnaJ homolog subfamily C member 3	0.013975	0.37	Reaction to stress, regulation of translation, stress of unfolded proteins
Ipo7	Importin-7	0.048261	0.31	Innate immune response, protein import into nucleus
Anxa5	Annexin A5	0.02236	−0.74	Calcium ion transmembrane transport, apoptosis
S100a9	Protein S100-A9	0.037099	−1.70	Apoptosis, autophagy, chemotaxis, immunity, inflammatory response, innate immunity