Figure 4.

Understanding the precise role of polyphenols as part of integrative therapy in IBD. By their anti-inflammatory properties, polyphenols have been shown to reduce inflammation in patients with Chron´s disease, while also affording protection to intestinal tissues and decreasing ulceration in those with ulcerative colitis. As a result, there is a growing utilization of polyphenols, as their administration offers improved outcomes and increases comfort for patients, especially when compared to conventional therapies. However, more investigations are needed to improve the effects of polyphenols such as their interaction with other drugs, or synergies with other biological compounds, and also the dosage and bioavailability of polyphenols.