Table 4.
Copper-based nanomedicines in cancer treatment
| Copper-based nanomedicines | Mechanism of anti-tumor | References |
|---|---|---|
| PCB | Induce cuproptosis | [125] |
| PHPM | Induce cuproptosis and remodel TME | [152] |
| MCD | Induce cuproptosis | [159] |
| CuET@PH NPs | Suppresses energy metabolism of CSCs and induce cuproptosis | [178] |
| DSF/MS-Cu-2 | Enhance efficacy of anti-CTLA-4 antibody | [237] |
| G5-PBA@CuS/cGAMP | Photothermal-triggered anti-tumor immune | [243] |
| Cu-THBQ/AX | Enhance anti-tumor immune | [208] |
| ES-Cu-MOF | Induce cuproptosis and ICD | [265] |
| PDA-DTC/Cu | Induce cuproptosis and ICD | [266] |
| Cel-Cu NP | Induce cuproptosis and ICD | [267] |
| PCD@Cu | Induce cuproptosis and ICD | [268] |
| SPNLCu | Deplete lactate, induce cuproptosis and ICD | [270] |
| mCGYL-LOx | Deplete lactate, induce cuproptosis and ICD | [271] |
| CAT-ecSNA-Cu | Alleviate hypoxia, induce cuproptosis and ICD | [272] |
| BAu-CuNCs | Induce cuproptosis and ICD | [273] |
| CCNAs | Enhance apoptosis, induce cuproptosis and ICD | [274] |
| MACuS | Induce cuproptosis and ICD | [275] |
| CHP | Reprogram TME, induce cuproptosis and ICD | [276] |