Table 1.
Correlation between WNT7B expression and OSCC clinicopathological factors
| Factors | Subtypes | Cases | WNT7B Low (%) | WNT7B High (%) | χ2 | P value |
|---|---|---|---|---|---|---|
| Gender | Male | 79 | 24(18.9%) | 55(43.3%) | 0.425 | 0.514 |
| Female | 48 | 12(9.4%) | 36(28.3%) | |||
| Age(years) | < 60 | 83 | 24(18.9%) | 59(46.5%) | 0.038 | 0.845 |
| ≥ 60 | 44 | 12(9.4%) | 32(25.2%) | |||
| Perineural invasion | Present | 48 | 8(6.3%) | 40(31.5%) | 5.183 | 0.023* |
| Absent | 79 | 28(22.0%) | 51(40.2%) | |||
| AJCC stages | I and II | 52 | 11(8.7%) | 41(32.3%) | 3.866 | 0.276 |
| III and IV | 75 | 25(19.7%) | 50(39.4%) | |||
| Differentiation | Well | 60 | 20(15.7%) | 40(31.5%) | 4.097 | 0.129 |
| Moderate | 20 | 2(1.6%) | 18(14.2%) | |||
| Poor | 47 | 14(11.0%) | 33(26.0%) | |||
| Lymph node metastasis | N0 and Nx | 72 | 27(21.3%) | 45(35.4%) | 6.858 | 0.009** |
| N1 and N2 | 55 | 9(7.1%) | 46(36.2%) |
AJCC, American Joint Committee on Cancer; Nx, unknow lymph node status; * P < 0.05, ** P < 0.01