Table 2.

Major features differentially expressed between POR and CARB during butyrate challenge (↓ downregulation/↑ upregulation) compared with results obtained from an artificially introduced porin loss (wt vs mt). Results observed in both systems are highlighted in bold, whereas those only significantly different between POR and CARB are given in standard font; individual regulation patterns for ATCC 8739 wild-type (wt) and ATCC 8739 ∆ompC/∆ompF (mt) are shown in brackets.

POR and CARB (mt and wt)	POR (mt)	CARB (wt)
↑Glutahionylspermidine synthase ↑Cysteine biosynthesis (mt±/wt±) ↓Iron acquisition and metabolism (mt↓ /wt↑) ↑Copper transport ↑Zinc transport (mt±/wt±) ↑Biotin biosynthesis	↑Acid stress response (mt±) ↑Universal stress protein family (mt±) ↑Oxidative stress response (mt±) ↑Periplasmic acid stress response (mt↓) ↓Branched-chain amino acid synthesis	↓Porins (lamB, ompC/F) ↑Stringent response