Table 1.
Significance of patient variables when assessing risk of pneumotoxicity according to Rheumatologists and Pulmonologists. LVF: left ventricular failure, pulm HTN: pulmonary hypertension, CAD: coronary artery disease, ILD: interstitial lung disease, BMI: body mass index, COPD: chronic obstructive pulmonary disease. P values calculated using Fisher’s exact test
| Combined n = 183 (%) | Rheumatologist n = 49 (%) | Pulmonologist n = 134 (%) | P value | |
|---|---|---|---|---|
| Age | 71 | 76 | 70 | ns |
| Smoking | 90 | 95 | 89 | ns |
| Underlying rheumatological condition | 89 | 93 | 87 | ns |
| Activity of rheumatological condition | 74 | 76 | 73 | ns |
| Cardiac comorbidities: LVF, cor pulmonale, pulm HTN, significant CAD | 76 | 86 | 75 | ns |
| Renal function | 74 | 73 | 74 | ns |
| Pre-existing ILD | 97 | 98 | 97 | ns |
| Static lung function | 93 | 91 | 94 | ns |
| Progression of ILD (1 yr) | 95 | 95 | 95 | ns |
| Change in static lung function (1 yr) | 90 | 86 | 92 | ns |
| Previous episode of pneumotoxicity | 75 | 70 | 77 | ns |
| Gender | 41 | 40 | 43 | ns |
| Ethnicity | 44 | 34 | 49 | < 0.05 |
| BMI | 46 | 64 | 40 | < 0.01 |
| COPD and/or emphysema | 55 | 79 | 45 | < 0.001 |
| Asthma | 28 | 38 | 24 | < 0.05 |
| Bronchiectasis | 57 | 71 | 51 | < 0.01 |
| Other respiratory comorbidities | 33 | 30 | 33 | ns |
| Diabetes Mellitus | 26 | 14 | 31 | < 0.05 |