Table 1. Baseline characteristics, medical history, time intervals, symptoms and vital signs of the investigated cohort.
Variables | All patients(n=1649) | ICH(n=373) | Other diagnoses(n=1276) | P value* |
Demographic | ||||
Age (years), median (IQR) | 71 (59–81) | 64 (55–76) | 72 (60–82) | <0.001† |
Number of male patients (relative number in %) | 947 (57.4%) | 250 (67.0%) | 697 (54.6%) | <0.001‡ |
Medical history | ||||
Hypertension | 1285 (77.9%) | 295 (79.1%) | 990 (77.6%) | 0.586‡ |
Diabetes mellitus | 365 (22.1%) | 70 (18.8%) | 295 (23.1%) | 0.087‡ |
Hyperlipidaemia | 773 (46.9%) | 133 (35.7%) | 640 (50.2%) | <0.001‡ |
Atrial fibrillation | 363 (22.0%) | 30 (8.0%) | 333 (26.1%) | <0.001‡ |
Coronary artery disease | 346 (21.0%) | 44 (11.8%) | 302 (23.7%) | <0.001‡ |
Prior IS | 108 (6.5%) | 11 (2.9%) | 97 (7.6%) | 0.002‡ |
Prior TIA | 151 (9.2%) | 23 (6.2%) | 128 (10.0%) | 0.030‡ |
Prior ICH | 23 (1.4%) | 9 (2.4%) | 14 (1.1%) | 0.098‡ |
Current alcohol use | 644 (39.1%) | 169 (45.3%) | 475 (37.2%) | 0.006‡ |
Time intervals | ||||
Onset-to-prehospital evaluation (mins), median (IQR) | 23 (14–42) | 23 (14–39) | 24 (14–43) | 0.232† |
Prehospital-to-hospital arrival (mins), median (IQR) | 32 (27–39) | 32 (27–39) | 33 (28–39) | 0.569† |
Onset-to-hospital arrival (mins), median (IQR) | 58 (46–79) | 58 (45–75) | 59 (46–80) | 0.154† |
Symptoms | ||||
Facial droop | 1406 (85.3%) | 320 (85.8%) | 1086 (85.1%) | 0.808‡ |
Grip weakness or lack of strength | 1526 (92.5%) | 363 (97.3%) | 1163 (91.1%) | <0.001‡ |
Arm weakness (drift or falls down) | 1499 (90.9%) | 367 (98.4%) | 1132 (88.7%) | <0.001‡ |
Unilateral weakness | 1645 (99.8%) | 373 (100.0%) | 1272 (99.7%) | 0.628‡ |
Decreased level of consciousness | 429 (26.0%) | 76 (20.4%) | 353 (27.7%) | 0.006‡ |
Improvement in neurological status | 528 (32.0%) | 62 (16.6%) | 466 (36.5%) | <0.001‡ |
Deterioration in neurological status | 92 (5.6%) | 50 (13.4%) | 42 (3.3%) | <0.001‡ |
Vital signs | ||||
SBP (mm Hg), median (IQR) | 160 (140–180) | 176 (160–194) | 155 (138–175) | <0.001† |
P- values were calculated using the Mann-Whitney U- test for continuous variables or the Chi-squareχ2 test for categorical variables to assess differences between ICH and other diagnoses; p- values less than 0.05 indicated statistical significance.
Mann-Whitney U test.
χ2 test
ICH, intracerebral haemorrhage; IS, ischaemic stroke; SBP, systolic blood pressure; TIA, transient ischaemic attack