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. 2024 Nov 1;105(11):002035. doi: 10.1099/jgv.0.002035

Table 2. Macroscopic and microscopic observations in WTEs subjected to necropsy.

WTE no.* Gender HPAIV subtype Observation Macroscopic finding Histological analysis In situ hybridization
4 Male H5N1 Observed alive exhibiting neurological symptoms and had difficulties flying; later found dead Hyperaemic skin around eyes and beak; empty gizzard and intestines Mild, multifocal lymphocytic and histiocytic myocarditis; multifocal splenic necrosis Positive signal in splenic necroses; few neurons positive in the brain
6 Female H5N5 Observed alive, exhibiting abnormal behaviour, not able to fly; euthanized Weight 5.5 kg;sparse content in gizzard Mild, multifocal lymphocytic and histiocytic myocarditis; multifocal splenic necrosis; mild encephalitis Few neurons positive in the brain
8 Unknown H5N1 Found dead Weight 6.5 kg; dark red lungs; empty gizzard; sparse content in intestines Multifocal to coalescing myocardial necrosis; mild encephalitis Positive signal in necrosis, myocytes and vessels in the heart; strong positive signal in neurons and vessels in the brain
12 Female H5N5 Found dead, with gunshot wounds Haemorrhages and perforations in muscles related to trauma; empty gizzard Mild, multifocal lymphocytic and histiocytic myocarditis; multifocal splenic necrosis; mild encephalitis Analysis not performed
*

The WTE no. relates to the numbering in Table S1.