Table 1.
Variable | Inactive (n = 571) | Active (n = 1237) | p-value |
---|---|---|---|
Age (years) | 70.8 ± 11.7 | 68.5 ± 12.5 | < 0.001 |
Male, % | 61 | 66 | 0.057 |
Current smoker, % | 12 | 10 | 0.151 |
Body mass index | 23.5 ± 4.3 | 23.5 ± 5.1 | 0.880 |
eGFR (ml/min/1.73m2) | 22.1 ± 10.4 | 24.1 ± 10.4 | < 0.001 |
Albumin(g/dl) | 3.9 ± 0.4 | 4.0 ± 0.4 | 0.016 |
Hemoglobin (g/dl) | 11.6 ± 1.7 | 12.0 ± 1.7 | < 0.001 |
Calcium (mg/dl) | 8.9 ± 0.6 | 9.0 ± 0.7 | 0.120 |
Phosphate (mg/dl) | 3.7 ± 0.8 | 3.6 ± 0.8 | 0.026 |
Intact PTH | 132 [85, 296] | 107 [69, 189] | 0.032 |
Proteinuria A3, % | 52 | 46 | 0.038 |
Transferrin saturation < 20%, % | 18 | 19 | 0.907 |
Ferritin < 100 ng/ml, % | 50 | 54 | 0.420 |
Complications | |||
Diabetes, % | 34 | 31 | 0.278 |
Hypertension, % | 89 | 87 | 0.318 |
Comorbidity score, out of 10* | 1.7 ± 1.0 | 1.6 ± 1.0 | 0.013 |
Medications, % | |||
Renin-angiotensin system inhibitors | 59 | 61 | 0.291 |
Antihypertensives(other) | 73 | 69 | 0.081 |
Statins | 38 | 43 | 0.066 |
SGLT2 inhibitors | 0.7 | 0.8 | 1.000 |
Erythropoiesis-stimulating agents | 36 | 29 | 0.008 |
Oral irons | 11 | 10 | 0.545 |
eGFR estimated glomerular filtration rates.
*The comorbidity score was calculated per patient as the number of comorbidities out of the following 10: coronary heart disease, hypertension, other cardiovascular disease, cerebrovascular disease, peripheral vascular disease, recurrent cellulitis/gangrene, neurologic disease, psychiatric disorder, gastrointestinal bleeding, and cancer15.