Table 2.
Adjusted incidence rates of renal outcomes and death by CKD stages, per 100 person-years.
| CKD Stage |
Renal outcome | Death | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Diabetic (n = 407) | Non-diabetic (n = 1,401) | Diabetic (n = 407) | Non-diabetic (n = 1,401) | |||||||||
| Active (n = 269)) | Inactive (n = 138) | IRR | Active (n = 968) | Inactive (n = 433) | IRR | Active (n = 269) | Inactive (n = 138) | IRR | Active (n = 968) | Inactive (n = 433) | IRR | |
| All | 20.0 (14.6, 27.2) | 23.0 (16.1, 32.9) | 0.87 (0.66, 1.14) | 9.1 (7.2, 11.4) | 8.8 (6.9, 11.1) | 1.03 (0.88, 1.22) | 3.6 (1.9, 7.0) | 4.2 (2.2, 8.1) | 0.86 (0.53, 1.38) | 0.8 (0.4, 1.6) | 1.5 (0.8, 2.7) | 0.57 (0.40, 0.79) |
| G3b | 6.3 (2.8, 14.0) | 10.2 (4.4, 23.5) | 0.61 (0.32, 1.19) | 2.5 (1.4, 4.5) | 3.3 (1.8, 6.0) | 0.77 (0.48, 1.21) | 2.2 (0.4, 11.2) | 1.2 (0.1, 13.1) | 1.82 (0.24, 14.11) | 0.5 (0.1, 1.7) | 0.7 (0.2, 2.5) | 0.72 (0.33, 1.56) |
| G4 | 14.2 (9.4, 21.6) | 15.6 (9.6, 25.3) | 0.91 (0.61, 1.36) | 9.8 (7.1, 13.5) | 8.8 (6.2, 12.4) | 1.12 (0.89, 1.41) | 4.4 (2.5, 7.9) | 4.1 (2.2, 7.6) | 1.08 (0.54, 2.19) | 1.0 (0.4, 2.4) | 2.2 (1.0, 5.1) | 0.43 (0.27, 0.68) |
| G5 | 88.1 (53.4, 145.4) | 91.6 (48.7, 172.5) | 0.96 (0.61, 1.51) | 36.4 (26.4, 50.4) | 34.0 (24.4, 47.5) | 1.07 (0.83, 1.39) | 1.7 (0.5, 6.6) | 2.6 (0.8, 8.5) | 0.65 (0.27, 1.57) | 0.6 (0.1, 2.2) | 0.8 (0.2, 2.7) | 0.73 (0.37, 1.44) |
IRR: incidence rate ratio in the active group compared with the inactive group (active/inactive).
The adjusted model includes adjustment for age, sex, smoking status, body mass index, eGFR, level of proteinuria, serum albumin, hemoglobin, diabetes, comorbidity score, cognitive heart failure, and lung disease. Renal outcome was defined as a 40% decline in eGFR from baseline, an eGFR of less than 10 ml/min/1.73m2, or end-stage kidney disease requiring dialysis or transplantation, whichever occurred first.
Significant values are given in italics.