Table 2.

Number of significant CpGs and Differentially Methylated Regions (DMRs) at FDR < 0.05 for the eight different analyses of trauma patients and elective surgical patients

Analysis		n	CpGs at FDR < 0.05	DMRs at HMFDR < 0.05	Lambda
1	pre-trauma vs. post-traumaa	5	8771	373	1.78
2	post-trauma vs. 30d-traumaa	60	10126	1169	1.67
3	pre-trauma vs. 30d-traumaa	5	18802	756	1.96
4	pre-surgery vs. post-surgerya	57	0	0	1.22
5	post-surgery vs. 30d-surgerya	57	0	0	1.15
6	post-trauma vs. post-surgery	117	344	22	1.19
7	30d-trauma vs. 30d-surgery	117	0	0	1.22
8	uncomplicated vs. complicated recovery, post-trauma/30d-traumaa	60	0/0	0/0	0.98/0.96

^apaired analysis.

FDR false discovery rate, HMFDR harmonic mean false discovery rate.