Table 3.

List of genes related to the top 20 differentially methylated regions (DMRs) in the analysis of the DNA methylation profile of patients post-trauma vs. 30d-trauma (analysis 2)

Gene ID(s)	Gene name(s)	hg19 genomic coordinates	No. of CpGs	Percent mean methylation difference	q-value
DUS2	Dihydrouridine Synthase 2	chr16: 68112968-68113598	2	2.2	1.14 × 10−7
VKORC1	Vitamin K Epoxide Reductase Complex Subunit 1	chr16:31105982-31107784	16	0.8	1.25 × 10−6
JAK1	Janus Kinase 1	chr1:65348569-65348727	2	3.9	1.48 × 10−6
MVD	Mevalonate Diphosphate Decarboxylase	chr16:88720046-88721033	4	2.3	1.59 × 10−6
BLM	BLM RecQ Like Helicase	chr15:91292460-91293212	5	-2.5	1.79 × 10−6
MTSS1	MTSS I-BAR Domain Containing 1	chr8:125698322-125698676	2	2.0	2.04 × 10−6
LPP LPP-AS1	LIM Domain Containing Preferred Translocation Partner In Lipoma LPP Antisense RNA 1	chr3:188285801-188287006	9	4.6	2.08 × 10−6
ITPR1 EGOT	Inositol 1,4,5-Trisphosphate Receptor Type 1 Eosinophil Granule Ontogeny Transcript	chr3:4790361-4791251	4	2.4	2.97 × 10−6
KCTD7 RABGEF1	Potassium Channel Tetramerization Domain Containing 7 RAB Guanine Nucleotide Exchange Factor 1	chr7:66255551-66256111	4	1.5	5.61 × 10−6
RAB11FIP1	RAB11 Family Interacting Protein 1	chr8:37731969-37732224	3	1.8	6.06 × 10−6
APMAP	Adipocyte Plasma Membrane Associated Protein	chr20:24968599-24968849	2	3.0	6.90 × 10−6
KMT2C	Lysine Methyltransferase 2C	chr7:151840170-151841181	3	-1.3	7.14 × 10−6
CCDC88C	Coiled-Coil Domain Containing 88C	chr14:91864095-91864737	2	0.3	8.34 × 10−6
SIK3	SIK Family Kinase 3	chr11:116942829-116943299	2	-2.0	8.34 × 10−6
USP36	Ubiquitin Specific Peptidase 36	chr17: 76789167-76789804	2	1.4	9.06 × 10−6
DGKD	Diacylglycerol Kinase Delta	chr2:234288623-234289457	6	1.2	9.22 × 10−6
AXIN1	Axin1	chr16:392436-392723	2	2.4	9.89 × 10−6
CALHM1	Calcium Homoeostasis Modulator 1	chr10:105217980-105219759	11	3.7	1.11 × 10−5
LINC00426	Long Intergenic Non-Protein Coding RNA 426	chr13:30947309-30948716	6	1.2	1.29 × 10−5
NMUR1	Neuromedin U Recepter 1	chr2:232393064-232393816	4	2.5	1.33 × 10−5