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. 2024 Oct 18;26:e60502. doi: 10.2196/60502

Table 5.

Depression symptom trajectories and time-varying effects of engagement with elements of blended care therapya.


Model 1 Model 2 Model 3

b (95% CI) P value b (95% CI) P value b (95% CI) P value
Intercept 12.90 (12.84 to 12.96) <.001 13.39 (13.33 to 13.46) <.001 13.59 (13.53 to 13.66) <.001
Weeks –1.45 (–1.46 to –1.43) <.001 –1.36 (–1.38 to –1.34) <.001 –1.23 (–1.25 to –1.21) <.001
Weeks² 0.07 (0.07 to 0.07) <.001 0.06 (0.06 to 0.06) <.001 0.05 (0.05 to 0.05) <.001
Therapy sessions last 7 days N/Ab N/A –0.76 (–0.80 to –0.72) <.001 –0.89 (–0.93 to –0.85) <.001
Digital lessons last 7 days N/A N/A –0.14 (–0.19 to –0.10) <.001 –0.12 (–0.16 to –0.08) <.001
Digital exercises last 7 days N/A N/A –0.31 (–0.36 to –0.26) <.001 –0.16 (–0.21 to –0.11) <.001
Provider feedback last 7 days N/A N/A –0.25 (–0.30 to –0.19) <.001 –0.15 (–0.21 to –0.10) <.001
Therapy sessions 8-14 days N/A N/A N/A N/A –0.67 (–0.71 to –0.62) <.001
Digital lessons 8-14 days N/A N/A N/A N/A –0.30 (–0.34 to –0.25) <.001
Digital exercises 8-14 days N/A N/A N/A N/A –0.05 (–0.10 to 0.01) .09
Provider feedback 8-14 days N/A N/A N/A N/A –0.08 (–0.14 to –0.02) .01
Deviance (–2LLc) 808,568.9 N/A 805,755.1 N/A 804,048.6 N/A
AICd 808,590.9 N/A 805,785.1 N/A 804,086.6 N/A
BICe 808,699.6 N/A 805,933.3 N/A 804,274.3 N/A

aThe outcome of interest was client scores on the Patient Health Questionnaire 9-item scale (PHQ-9). The analyzed sample included 22,070 individuals with a baseline PHQ-9 score of ≥10. dfresidual=144,505 for model 1, dfresidual=144,501 for model 2, and dfresidual=144,497 for model 3.

bNot applicable.

c–2LL: –2 × log likelihood.

dAIC: Akaike information criterion.

eBIC: Bayesian information criterion.