Table 2. Composition of GE-BM and data of Vesicle size and entrapment efficiency .
Formulation code | Bile salt (mg) | Edge activator (% v/v) | Surfactant (% w/v) | VS (nm) | EE (%) | ||
Practical* | Predicted | Practical* | Predicted | ||||
GE-BM-1 | 10.00 | 0.25 | 2.00 | 234.7 ± 7.2 | 239.03 | 71.53 ± 2.61 | 71.05 |
GE-BM-2 | 30.00 | 0.25 | 2.00 | 373.5 ± 11.7 | 382.02 | 52.47 ± 1.93 | 52.91 |
GE-BM-3 | 18.10 | 0.55 | 2.00 | 321.5 ± 9.1 | 326.77 | 67.72 ± 2.15 | 67.08 |
GE-BM-4 | 30.00 | 0.75 | 2.00 | 380.9 ± 5.6 | 381.83 | 52.91 ± 2.82 | 53.35 |
GE-BM-5 | 30.00 | 0.75 | 2.00 | 385.9 ± 9.4 | 381.83 | 53.91 ± 2.68 | 53.35 |
GE-BM-6 | 20.10 | 0.30 | 2.20 | 318.5 ± 12.4 | 297.68 | 62.23 ± 1.81 | 63.34 |
GE-BM-7 | 10.00 | 0.75 | 2.70 | 210.4 ± 6.5 | 205.69 | 74.5 ± 3.27 | 74.52 |
GE-BM-8 | 21.70 | 0.75 | 2.83 | 250.7 ± 7.8 | 259.13 | 63.13 ± 2.42 | 63.46 |
GE-BM-9 | 10.50 | 0.46 | 2.83 | 201.2 ± 5.9 | 204.30 | 73.42 ± 1.56 | 73.98 |
GE-BM-10 | 28.10 | 0.30 | 3.00 | 263.9 ± 7.5 | 262.73 | 64.62 ± 8 | 62.37 |
GE-BM-11 | 18.10 | 0.25 | 3.19 | 185.3 ± 4.3 | 189.62 | 70.21 ± 2.92 | 70.49 |
GE-BM-12 | 30.00 | 0.55 | 3.19 | 287.4 ± 7,8 | 284.30 | 59.94 ± 2.32 | 60.68 |
GE-BM-13 | 21.70 | 0.46 | 3.95 | 217.6 ± 5.3 | 223.31 | 75.32 ± 2.43 | 75.23 |
GE-BM-14 | 30.00 | 0.25 | 4.00 | 207.4 ± 6.8 | 205.94 | 74.63 ± 1.65 | 75.25 |
GE-BM-15 | 10.00 | 0.42 | 4.00 | 181.3 ± 4.6 | 178.29 | 81.42 ± 2.32 | 81.22 |
GE-BM-16 | 23.00 | 0.75 | 4.00 | 237.8 ± 8.9 | 235.52 | 69.64 ± 1.84 | 69.34 |
*Values are expressed as mean ± SD, n = 3.