Table 6. In vitro characterization parameters of developed in situ gel .

Code	Clarity	% Transmission	Viscosity		Gelling strength		Drug content
			Sol state (pH5.4±0.2)	Gel state (STF, pH 7.4±0.2)	Sol (pH5.4±0.2)	Gel (STF, pH 7.4±0.2)
GE-BMopt-IG1	Transparent	97.53	13.42	45.12	--	-	96.65 ± 2.75
GE-BMopt-IG2	Transparent	96.32	28.53	165.43	-	+	97.43 ± 1.92
GE-BMopt-IG3	Transparent	95.25	66.76	246.71	-	+ +	97.91 ± 2.03
GE-BMopt-IG4	Transparent	87.98	105.34	387.23	-	+ + +	99.16 ± 1.02
GE-BMopt-IG5	Translucent	80.43	187.92	687.54	+	+ + + +	99.72 ± 0.48

(-) No gel formation, ( + ) gel formed in 1min and dissolved within 30min, ( + + ) gel for in few seconds and dissolved in 2 h, ( + + + ) gel formed quickly and stayed > 24 h, ( + + + + ) gel formed very quickly and stayed for > 24 h (very hard gel).