Correction: Intracytoplasmic stable expression of IgG1 antibody targeting NS3 helicase inhibits replication of highly efficient hepatitis C Virus 2a clone

Correction: Virology Journal 2010, 7:118 http://www.virologyj.com/content/7/1/118

Following publication of the original article [1], the authors identified that an image in Fig. 6 under column 24, row Huh-7.5 expressing a control antibody also was published in a separate Virology Journal article, “Impaired antiviral activity of interferon alpha against hepatitis C virus 2 in Huh-7 cells with a defective Jak-Stat pathway,” S. Hazari et al., Virology Journal 2010, 7:36. 10.1186/1743-422X-7-36. This duplicated image appears in Fig. 8 under column 24, row IFN-alpha(+) in S. Hazari et al. I am the corresponding author on this S. Hazari et al. publication and will request that the duplicated image in Fig. 8 be deleted from this publication in a separate letter.

The incorrect Figure is:

The incorrect Figure legend.

Figure 6: Infectivity assay of HCV-GFP chimera virus in Huh-7.5 cells expressing NS3 antibody and control antibody. Huh-7.5 cells (1 × 10⁴) were seeded on a 2-well glass chamber slide, next day infected with JFH1-GFP virus for overnight at 37°C. Infected cells were examined for GFP expression after 24, 48, 72 and 96 h of post infection. Superimposing blue (nucleus) with green fluorescence (HCV GFP) using the Abode Photoshop computer software generated the final image. Upper panel: shows HCV-GFP expression in Huh-7.5 cells infected with JFH1 virus. Middle panel: shows HCV-GFP expression was terminated in Huh-7.5 cells expressing NS3 antibody. Lower panel: shows no reduction in the level of HCV-GFP expression in Huh-7.5 cells expressing control antibody.

The correct Figure is:

The correct Figure legend.

Figure 6: Infectivity assay of HCV-GFP chimera virus in Huh-7.5 cells expressing NS3 antibody and control antibody. Huh-7.5 cells (1 × 10⁴) were seeded on a 2-well glass chamber slide, next day infected with JFH1-GFP virus for overnight at 37°C. Infected cells were examined for GFP expression after 48, 72 and 96 h of post infection. Superimposing blue (nucleus) with green fluorescence (HCV GFP) using the Abode Photoshop computer software generated the final image. Upper panel: shows HCV-GFP expression in Huh-7.5 cells infected with JFH1 virus. Middle panel: shows HCV-GFP expression was terminated in Huh-7.5 cells expressing NS3 antibody. Lower panel: shows no reduction in the level of HCV-GFP expression in Huh-7.5 cells expressing control antibody.