Figure 2.
Ventricular arrhythmia events detected after injection of hiPSC-CLs. (A) Experimental design evaluating cardiac effects of hiPSC-CLs in 28 monkeys. Representative electrocardiogram (ECG) tracings: (B) normal sinus rhythm, (C) supraventricular tachycardia, (D) premature ventricular contractions (black arrows), (E) ventricular couplet (black arrow), (F) intermittent, non-sustained ventricular tachycardia (VT), and (G) incessant VT. (H) Frequency and duration of all VT events in the five affected subjects. PAB, pulmonary artery banding; ICM, implantable cardiac monitor.