Table 1.
Total number of severe autoimmune diseases in women with premature ovarian insufficiency (POI) (n = 3972) and in the reference cohort (N = 15 708), prior to the index datea and during the whole study period.b
| Prior the index datea |
During the whole study periodb |
|||
|---|---|---|---|---|
| Number of autoimmune diseases | Women with POI n (%) | Reference cohort n (%) | Women with POI n (%) | Reference cohort n (%) |
| 0 | 3749 (94.4) | 15 352 (97.7) | 3469 (87.3) | 14 624 (93.1) |
| 1 | 194 (4.9) | 338 (2.2) | 409 (10.3) | 999 (6.4) |
| 2 | 27 (0.7) | 17 (0.1) | 77 (1.9) | 77 (0.5) |
| ≥3 | <5 (<0.1) | <5 (<0.03) | 17 (0.4) | 8 (0.1) |
a
The date when reimbursement for hormone replacement therapy (HRT) was granted for the case with POI.
b
By the end of the year 2017, the date of migration, or the date of death.