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. 2024 Jun 6;109(11):3641–3649. doi: 10.3324/haematol.2023.284953

Figure 5.

Figure 5.

Genetic alterations at initial onset and after central nervous system progression. Number of pathogenic genetic alterations in vitreous humor samples taken at disease onset and brain tissue biopsy samples taken after central nervous system (CNS) progression per case. Concordant alterations (found in both vitreous humor and brain tissue) and discordant alterations (found in either vitreous humor or brain tissue) are indicated.