Figure 1.

Vaginal microbiota composition of Native American women in our study. Bar plots show the relative abundance of taxa assigned to the A, genus or B, species level grouped based on race. Vaginal microbiota profiles were similar between Native American and non-Native American women from Northern Arizona. The most prevalent Lactobacillus species included Lactobacillus crispatus and Lactobacillus iners. Dysbiotic Lactobacillus-depleted profiles consisted of typical communities of anaerobic bacteria associated with bacterial vaginosis (BV), including Gardnerella vaginalis [assigned as Bifidobacterium vaginale in the Genome Taxonomy Database (GTDB)], Fannyhessea vaginae (formerly known as Atopobium vaginae), Sneathia vaginalis (formerly known as Sneathia amnii), Prevotella timonensis, Megasphaera lornae (assigned as 28L sp00017755 in GTDB), and Clostridiales genomosp. BVAB1 (assigned as UBA629 sp005465875 in GTDB).