Table 3.
Terminalia brownii leaf lectin (TerBLL) antinociceptive effect and pain relief caused by intraperitoneal administration of acetic acid (0.7 %).
| Groups |
Dose |
Average mice weight |
Abdominal writhing |
Pain inhibition |
One-Way ANOVA |
Tuckey HSDa |
||
|---|---|---|---|---|---|---|---|---|
| (n = 5) | (mg/Kg) | (kg) | (M ± S.D.) | (%) | F | P value | P value | 95 % CI |
| G1 | Acetic acid (0.7 %) | 25.26 ± 4.2 | 50.2 ± 32.4 | 0.0 | 7.428 | 0.001 | - | - |
| G2 | TerBLL (3 mg/kg) | 27.82 ± 4.1 | 12.3 ± 16.9 | 75.4 | 0.016 | 5.7–70.1 | ||
| G3 | TerBLL (6 mg/kg) | 30.02 ± 2.3 | 0.0 ± 0.0 | 100 | 0.001 | 17.9–82.4 | ||
| G4 | TerBLL (12 mg/kg) | 28.12 ± 3.1 | 9.8 ± 10.8 | 80.5 | 0.010 | 8.2–72.6 | ||
| G5 | Diclofenac Na (10) | 24.72 ± 4.2 | 0.0 ± 0.0 | 100 | 0.001 | 17.9–82.4 | ||
a
Post hoc analysis was performed at the 0.05 significance level; comparisons were performed between G1 (the negative control) and the test groups (G2 – G5); bold numbers represent significant results at P0.05.