Fig. 2.

(A) Small RNA sequencing (sRNA‐Seq) heatmap of the differentially expressed miRNAs (DEMs) associated with progression‐free survival (PFS) in dogs with diffuse large B‐cell lymphoma (DLBCL). Red represents high expression; blue represents low expression. The color intensity from red to blue represents the log‐expression values for each miRNA when converted to standard normal deviation (Z scores). The samples with short PFS are DLBCL1,3,5 (n = 3) and those with DLBCL with long PFS survival are DLBCL 2,4,6 (n = 3). The miRNAs with greater than three‐fold expression differences (i.e., log FC > 1.58) and adjusted P‐values < 0.01 were selected. (B) The small RNA‐seq volcano plot of the differentially expressed miRNAs (DEMs). Red represents high expression; blue represents low expression. The miRNAs with greater than three‐fold expression differences (log₂FC > 1.58) and (−log₁₀ adj P‐values < 0.01 = 2).