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. 2024 Sep 1;14(11):1899–1913. doi: 10.1002/2211-5463.13887

Table 3.

Differences in mean miRNA expression among three phenotypic groups based on progression‐free survival (PFS) and clinical best overall response (BOR) classifications. Dogs were in the high‐risk (partial remission group n = 12), complete remission with low survival (intermediate‐risk group n = 14), and complete remission with high survival (low‐risk group n = 18) in 44 canine lymphoma cases.

miRNA df F a Raw P FDR P Low risk vs other b Low vs high‐risk Low vs intermediate Intermediate vs low risk
d c P d d P d P d P
hsa‐miR‐192‐5p 2, 22.9 7.809 0.0026 0.0299 −1.184 0.001 −1.03 0.032 −1.301 0.005 0.15 0.708
hsa‐miR‐16‐5p 2, 25.4 7.521 0.0027 0.0299 −1.137 0.002 −1.25 0.005 −1.107 0.012 0.325 0.407
hsa‐miR‐29c‐3p 2, 19.1 5.274 0.015 0.0886 0.4 0.336 −0.22 0.595 1.179 0.021 −0.953 0.08
cfa‐miR‐196b 2, 23.5 4.945 0.0161 0.0886 −0.531 0.268 −0.14 0.724 −1.05 0.021 0.682 0.268
cfa‐miR‐101 2, 22.1 4.401 0.0246 0.0902 −0.774 0.036 −0.56 0.358 −1.047 0.03 0.16 0.695
bta‐miR‐99a‐5p 2, 23.5 4.224 0.0271 0.0902 −0.631 0.079 −1.13 0.038 −0.177 0.624 −0.988 0.07
hsa‐miR‐590‐3p 2, 23.7 4.138 0.0287 0.0902 −0.651 0.12 −0.36 0.644 −1.009 0.028 0.412 0.644
hsa‐miR‐152‐3p 2, 24.6 3.624 0.0417 0.1045 −0.804 0.046 −0.96 0.058 −0.661 0.154 −0.292 0.466
bta‐miR‐195 2, 26 3.568 0.0427 0.1045 −0.839 0.041 −0.87 0.079 −0.799 0.079 −0.05 0.9
cfa‐miR‐125a 2, 24.5 3.428 0.0487 0.1072 −0.808 0.046 −0.9 0.085 −0.712 0.106 −0.335 0.412
cfa‐miR‐889 2, 25.2 2.993 0.0682 0.1364 −0.755 0.077 −0.68 0.168 −0.816 0.084 0.059 0.884
hsa‐miR‐187‐3p 2, 26.1 2.839 0.0766 0.1405 −0.657 0.132 −0.88 0.092 −0.459 0.384 −0.533 0.384
hsa‐miR‐130b‐3p 2, 25.6 2.672 0.0883 0.1495 −0.398 0.449 −0.7 0.189 −0.135 0.696 −0.84 0.189
cfa‐miR‐23a 2, 23 2.383 0.1147 0.1802 −0.318 0.572 −0.75 0.223 0.193 0.592 −0.888 0.169
hsa‐miR‐127‐3p 2, 24.3 2.129 0.1406 0.2061 −0.639 0.166 −0.64 0.263 −0.631 0.263 −0.087 0.828
hsa‐miR‐129‐5p 2, 26.8 1.838 0.1787 0.2457 −0.6 0.259 −0.5 0.33 −0.671 0.259 0.305 0.439
hsa‐miR‐9‐5p 2, 26.8 1.56 0.2286 0.2903 −0.191 1 −0.52 0.555 0.05 1 −0.595 0.555
hsa‐miR‐361‐5p 2, 22 1.536 0.2375 0.2903 −0.245 0.815 0.057 0.888 −0.615 0.407 0.473 0.758
hsa‐miR‐128‐3p 2, 23.6 1.389 0.2691 0.3116 0.17 1 −0.18 1 0.507 0.592 −0.595 0.592
hsa‐miR‐381‐3p 2, 24.7 1.27 0.2984 0.3282 −0.408 0.585 −0.61 0.489 −0.211 0.585 −0.491 0.585
cfa‐miR‐411 2, 24.5 1.086 0.3534 0.3702 −0.451 0.589 −0.41 0.589 −0.481 0.589 −0.01 0.98
cfa‐miR‐1840 2, 24.8 0.953 0.3991 0.3991 −0.413 0.737 −0.34 0.751 −0.474 0.737 0.078 0.847
a

Welch's one‐way ANOVA with unequal variances.

b

“Other” pools intermediate risk and high risk.

c

Cohen's d using the average variance of the contrasted groups.

d

Bonferroni‐Holm adjusted P‐value for contrast in the group means.

Values in bold are statistically significant.