TABLE 2.

Cox analysis of overall survival.

Variable	Univariate analysis		Multivariate analysis
	HR (95% CI)	p Value	HR (95% CI)	p Value
GLYAT expression
Low (n = 166) vs. high (n = 69)	1.943 (1.086–3.476)	0.025	2.184 (1.205–3.959)	0.010
Age
<60 (n = 125) vs. ≥60 (n = 110)	1.201 (0.762–1.891)	0.43
Gender
Male (n = 161) vs. Female (n = 74)	0.778 (0.487–1.244)	0.294
Histologic grade
G1–G2 (n = 132) vs. G3–G4 (n = 103)	1.071 (0.678–1.690)	0.769
TNM stage
I (n = 113) vs. II–IV (n = 122)	1.276 (1.128–1.443)	<0.001	1.103 (0.937–1.299)	0.239
T stage
T1–T2 (n = 167) vs. T3–T4 (n = 68)	3.103 (1.967–4.896)	<0.001	2.561 (1.379–4.756)	0.003
N stage
N0 (n = 231) vs. N1 (n = 4)	2.064 (0.504–8.448)	0.313
M stage
M0 (n = 231) vs. M1 (n = 4)	3.925 (1.230–12.522)	0.021	1.505 (0.456–4.967)	0.502

Note: Statistically significant p values are given in bold, P < 0.05.

Abbreviations: CI, confidence interval; GLYAT, Glycine N‐acyltransferase; HR, hazard ratio; TNM, tumour‐node‐metastasis.