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. Author manuscript; available in PMC: 2024 Nov 4.
Published in final edited form as: Nat Aging. 2023 May 25;3(7):846–865. doi: 10.1038/s43587-023-00420-2

Extended Data Fig. 3 |. Senescent female Znrf3 cKO adrenal glands activate production of cytokines and growth factors.

Extended Data Fig. 3 |

(a) URA using RNA-seq data predicts significantly activated and inhibited cytokines in 9-week and (b) week female Znrf3 cKO adrenal tissue compared to 6-week, p < 0.05. (c) URA predicts significantly activated and inhibited growth factors in 9-week and (d) 12-week female Znrf3 cKO adrenal tissue compared to 6-week, p < 0.05. Data is representative of 4 biological replicates per group, statistical analysis in IPA was performed using a right-tailed fishers exact test, p < 0.05.