Fig. 3.

Blood cell count of females and male diethylnitrosamine (DEN) − treated C3H mice. Count of monocytes (a), lymphocytes (b), neutrophils (c), and neutrophil-to-lymphocyte ratio (NLR) (d). Data were expressed as mean (10⁹/L) ± SEM of cell number. Statistical comparison among female and male groups at the same time: ^#P<0.05; ^##P<0.01; ^###P<0.001. All statistical analyses of this figure were performed using ANOVA followed by the Tukey test. Due to the lack of significant changes observed in the control groups euthanized on day 210 and day 300, the data from the controls on day 210 is depicted in the figure for simplification purposes.