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. 2024 Oct 22;11:1442276. doi: 10.3389/fmed.2024.1442276

Table 2.

The incidence of HFRS complicated with AP in different subgroups.

Subgroup No. of studies r(%) 95%CI for r Heterogeneity Begg’s test Egger’s test Meta-regression
I2(%) p Z p t p t p
Gender
Male 6 9.4 5.7–13.1 61.1 0.017 1.05 0.293 2.25 0.060 0.460 0.656
Female 6 10.8 5.6–16.0 29.5 0.225 0.49 0.624 1.89 0.115
Sample size
<100 6 6.2 3.4–9.0 0.0 0.466 1.69 0.091 2.05 0.400 0.910 0.386
≥100 5 9.9 5.9–14.0 78.8 0.001 1.96 0.50 4.92 0.039
Location
Asia 9 8.2 5.4–11.0 65.5 0.003 1.88 0.061 1.97 0.180 0.670 0.520
Europe 2 11.6 4.0–19.1 0.0 0.896 1.00 0.317 2.28 NA
Research design
Case–control study 3 11.0 5.6–16.4 68.7 0.041 1.57 0.117 2.76 0.478 −1.090 0.305
Cross-sectional study 8 7.3 4.4–10.3 49.0 0.056 1.48 0.138 1.75 0.106
Quality of study
Medium 2 8.2 4.3–12.2 0.0 0.466 1.00 0.317 1.82 NA −0.080 0.935
High 9 8.6 5.5–11.7 66.3 0.003 1.67 0.095 1.25 0.169

NA, not applicable. In the meta-regression analysis, the reference groups were Male, <100, Asia, Case–control study, Medium, respectively.