Table 1.

Selected key nodes with topological coefficients

Term	Tn	p-Value*	UNIQUER_ID
Cytochrome c-mediated apoptotic response	1.0	0.0307	HSA:111461
COPI-mediated anterograde transport	1.0	0.0323	HSA:6807878
Membrane Trafficking	0.95	0.0171	HSA:199991
Vesicle-mediated transport	0.95	0.0099	HSA:5653656
Laminin interactions	0.93	0.0298	HSA:3000157
Apoptosis	0.92	0.0322	HSA:109581
Programmed Cell Death	0.92	0.0487	HSA:5357801
Disorders of Nervous System Development	0.87	0.0330	HSA:9697154
Asparagine N-linked glycosylation	0.84	0.0281	HSA:446203
Intrinsic Pathway for Apoptosis	0.75	0.0364	HSA:109606
Apoptotic factor-mediated response	0.75	0.0281	HSA:111471
Signaling by RAS mutants	0.52	0.0459	HSA:6802949
Paradoxical activation of RAF signaling by kinase inactive BRAF	0.52	0.0459	HSA:6802955
Signaling downstream of RAS mutants	0.52	0.0459	HSA:9649948
Signaling by RAF1 mutants	0.52	0.0351	HSA:9656223
Axon guidance	0.50	0.0167	HSA:422475

T_n: topological coefficient (T_n = avg (J(n,m)) / k_n.).

*p Value: Corrected with Benjamini-Hochberg.